课题组简介：

   陈涛教授课题组是“浙江省药用植物种质改良与质量控制技术重点实验室”和“浙江省药用植物生物技术国际合作基地”的核心团队之一。本课题组长期从事植物逆境胁迫与生长发育研究。以水稻、向日葵、药用植物等为研究对象，立足于鉴定调控植物耐逆、产量、活性成分合成的主要基因，发现其信号传导途径及遗传调控网络，解析调控逆境胁迫影响作物产量、药用活性成分的分子机理，进而挖掘作物及药用植物的遗传资源潜力，为高产育种和高品质育种提供理论基础和基因资源。在Nature Communications、Molecular Plant、Plant Cell、Nucleic Acids Research、Plant Physiology等国际著名期刊杂志发表多篇文章。课题组先后承担国家自然科学基金项目5项，国家重点研发计划项目子课题1项，国家重大专项子任务1项，省级自然基金及重点研发计划课题3项。

课题组照片：

课题组负责人：陈涛

课题组成员

教师：张俊成、蔡茂红、 梁良

学生：韩雨良、张思琦、孙明哲、谢沁钰、王颖薇、曾琴宗、陈有恒、张宇童、王陈畅、陆玲悦

主要研究方向

1. 植物耐逆性形成的分子机制

逆境胁迫是造成作物减产的重要因素。随着全球气候变化的加剧，土壤盐渍化和极端温度等都对作物高产稳产造成了严重的挑战。团队通过综合生物化学、分子生物学、遗传学、植物生理学等多种手段解析了植物在多水平多维度对耐逆性的调控机制。发表了多篇高水平研究论文（Int. J. Biol. Macromol. 2023; Int. J. Mol. Sci. 2022;New Phytologist，2021; Plant Cell, 2016; Nucleic Acids Research, 2015）

2. 作物重要农艺性状形成的遗传调控网络

优质高效、高产稳产是作物育种所追求的目标。团队利用突变体材料、优异种质资源、定向突变库等资源，解析了调控作物株型、粒形、花期、产量等多个关键性状的遗传调控机制。发表了多篇高水平研究论文(Crop Journal, 2023; Int. J. Mol. Sci. 2023; Journal of Plant Biology, 2022; Molecular Plant,2021; Nature Communications,2021; Plant Physiology, 2018)

3. 作物高产优质耐逆新品种的分子改良

分子聚合育种是未来发展方向。相较于传统育种，分子聚合育种能极大地缩短育种周期，加速品种迭代，培育更能适应环境变化的智能作物。团队在解析向日葵抗列当的分子机制基础上，利用开发的分子标记极大地缩短了育种进程。与新疆农科院共同培育抗列当品种2399，通过了国家向日葵新品种登记。

代表性成果：

1. 与新疆农科院等单位合作育成的向日葵新品种2399获得新品种登记，推广面积累计达200万亩，农户累计增收约4亿元。

2. Teng, Y., Cai, M., Xie, Q., Liu, Q., Zhang, H., Chen, T. (2023) BEAR1, a bHLH transcription factor, controls seedling growth by regulating gibberellins biosynthesis in rice. The Crop Journal, doi:https://doi.org/10.1016/j.cj.2023.02.007

3. Zhang, X., Xie, Q., Xiang, L., Lei, Z., Huang, Q., Zhang, J., Cai, M., Chen, T. (2023) AtSIEK, an EXD1-like protein with KH domain, involves in salt stress response by interacting with FRY2/CPL1. Int. J. Biol. Macromol. 233:123369.

4. Sun, M., Cai, M., Zeng, Q., Han, Y., Zhang, S., Wang, Y., Xie, Q., Chen, Y., Zeng, Y., Chen, T. (2023) Genome-Wide Identification and Expression Analysis of UBiA Family Genes Associated with Abiotic Stress in Sunflowers (Helianthus annuus L.) Int. J. Mol. Sci. 24(3):1883.

5. Han, Y., Cai, M., Zhang, S., Chai, J., Sun, M., Wang, Y., Xie, Q., Chen, Y., Wang, H., Chen, T. (2022) Genome-Wide Identification of AP2/ERF Transcription Factor Family and Functional Analysis of DcAP2/ERF#96 Associated with Abiotic Stress in Dendrobium catenatum. Int. J. Mol. Sci. 23, 13603.

6. Teng, Y., Lv, M., Zhang, X., Cai, M., Chen, T. (2022) BEAR1, a bHLH Transcription Factor, Controls Salt Response Genes to Regulate Rice Salt Response. Journal of Plant Biology 65:217–230.

7. Cai, M., Zhu, S., Wu, M., Zheng, X., Wang, J., Zhou, L., Zheng, T., Cui, S., Zhou, S., Li, C., Zhang, H., Chai, J., Zhang, X., Jin, X., Cheng, Z., Zhang, X., Lei, C., Ren, Y., Lin, Q., Guo, X., Zhao, L., Wang, J., Zhao, Z., Jiang, L., Wang, H., Wan, J. (2021) DHD4, a CONSTANS-like family transcription factor, delays heading date by affecting the formation of the FAC complex in rice. Molecular Plant 14(2):330-343.

8. Zhang, J., Zhang, D., Fan, Y., Li, C., Xu, P., Li, W., Sun, Q., Huang, X., Zhang, C., Wu, L., Yang, H., Wang, S., Su, X., Li, X., Song, Y., Wu, M., Lian, X., Li, Y. (2021) The identification of grain size genes by RapMap reveals directional selection during rice domestication. Nature Communications 12(1):5673.

9. Cheng, X. ^#, He, Q. ^#, Tang, S. ^#, Wang, H., Zhang, X., Lv, M., Liu, H., Gao, Q., Zhou, Y., Wang, Q., Man, X., Liu, J., Huang, R., Wang, H.^*, Chen, T. ^*, Liu, J. ^* (2021) The miR172/IDS1 signaling module confers salt tolerance through maintaining ROS homeostasis in cereal crops. New Phytologist 230:1017-1033.